Fetal metabolism and fetal growth

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Exogenous GH infusion to late-gestational fetal sheep does not alter fetal growth and metabolism.

The role of GH in the regulation of fetal growth and metabolism in late gestation is not well defined. The aim of this study was to determine the effects of exogenous GH infusion on fetal growth and feto-placental metabolism in the normally growing late-gestation fetal sheep. Eleven fetuses received pulsatile GH infusion (3.5 mg/day) for 10 days while 12 control fetuses received vehicle. The GH...

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Fetal insulin and growth hormone metabolism in the subhuman primate.

The concentrations of plasma glucose, insulin, growth hormone, and immunoreactive growth hormone-like substance in subhuman primate fetal and maternal plasma were examined after the intravascular administration of glucose, arginine, or tolbutamide to the fetus. Cannulation of interplacental vessels permitted studies on the fetus in utero without disruption of fetal-placental-maternal anatomic i...

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Maternal Lipid Metabolism and Its Implications for Fetal Growth

During gestation, the mother has to adapt her own metabolism to support a continuous extraction of nutrients through the placenta to sustain fetal development. Quantitatively, glucose and amino acids are the most abundant of these nutrients crossing the placenta (1,2), and the continuous dependence of the fetus on these compounds is well-known. However, the placenta is practically impermeable t...

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Studies in fetal metabolism.

The origin of the constituents of the mammalian fetus has been the subject of controversy, the literature of which has been exhaust,ively reviewed by Needham (1, 2) and Huggett (3). Two processes come into consideration: transplacental absorption from the maternal circulation and synthesis in t,he tissues of the fetus proper. In regard to the transplacental passage of fat,ty acids, the most imp...

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Fetal Bile Salt Metabolism

Comparison with the results of similar experiments in adult dogs showed that the fetal liver was almost as efficient as the adult liver in the uptake, conjugation, and excretion of tracer amounts of cholate-"C. The maximal rate of excretion of radiolabel attained by the fetus was somewhat slower than in the adult (82.8 ±1.4% and 96.1 ±4.0% [mean +SE] of the infusion rate, respectively), and the...

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ژورنال

عنوان ژورنال: Reproduction

سال: 1976

ISSN: 1470-1626,1741-7899

DOI: 10.1530/jrf.0.0470189